194
Compulsory

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The goal of this course is to give an introduction to the most important mathematical and algorithmic ideas underlying the constraint-based analysis of genome-scale metabolic networks, with applications to systems biology and biotechnology.


We will discuss the steady-state flux cone, flux balance analysis (FBA), flux variability analysis (FVA), flux coupling analysis (FCA), thermodynamic constraints, elementary flux modes (EFMs), and optimality principles for metabolic regulation. On the algorithmic side, the focus will be on linear and mixed-integer optimisation methods.

The goal of this course is to give an introduction to the most important mathematical and algorithmic ideas underlying the constraint-based analysis of genome-scale metabolic networks, with applications to systems biology and biotechnology.


We will discuss the steady-state flux cone, flux balance analysis (FBA), flux variability analysis (FVA), flux coupling analysis (FCA), thermodynamic constraints, elementary flux modes (EFMs), and optimality principles for metabolic regulation. On the algorithmic side, the focus will be on linear and mixed-integer optimisation methods.

Cross-language

194 018
Compulsory

Expectant Mother

Not dangerous
Partly dangerous
Alternative Course
Dangerous

Nursing Mother

Not dangerous
Partly dangerous
Alternative Course
Dangerous

AncillaryCourses

Übung zu Metabolische Netzwerke

Expectant Mother

Not dangerous
Partly dangerous
Alternative Course
Dangerous

Nursing Mother

Not dangerous
Partly dangerous
Alternative Course
Dangerous