Sequenzanalyse S18
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Description

Information for students

This is an elective course (Wahlpflichtveranstaltung) for students in the MSc Bioinformatics. As opposed to the recent years, we will use the KVV Sakai system as an exchange platform.

The modul consists of a lecture, a seminar and exercises which will be blocked according to the respective optic. This means we will have first several lectures, followed by exercises, followed by seminars. One block is concluded with a review test about the content.

Content: We will deal with methods for approximate searching and variant detection in sequences, the construction and use of modern index structures and methods for RNA sequence analysis and variant detection.

Requirements for "aktive Teilnahme":

  • You have to be prepared to give a seminar talk (if it's your group's turn).
  • In addition you need to reach 50% of all points of the reviews.

Seminar group A: Pluhatsch,Krüger,Gottlieb,
Seminar group B: Seiler, Dawid
Seminar group C: Kim, Heinig, Darvish

Content

Date   Event
17.4.  L: Organisation, Rehearsal suffix array construction and search 
19.4.  L: Linear time lcp computation
20.4.  Exercise
24.4.  S: Two Space Saving Tricks for Linear Time LCP Array Computation (A)
26.4.  Review 1
27.4.  L: Linear time construction with the SKEW algorithm 
3.5.  L: Lazy suffix trees
4.5. Exercise
8.5.  S: DisLex a transformation for discontiguous suffix array construction (B)
10.5.  Holiday
11.5.  Exercise
15.5.   S: An incomplex algorithm for fast suffix array construction (C)
17.5  Review 2
18.5  L: Burrows Wheeler transform 1
22.5.  L: Burrows Wheeler transform 2
24.5.  L: Burrows Wheeler transform 3
25.5.  Exercise
29.5.  S: FMtree: A fast locating algorithm of FM-indexes for genomic data (A)
31.5.  S: HT short read alignment via the bidirectional BWT (B)
1.6.  Review 3 
5.6.

 L: Factor filters

7.6.  L: 01*0 Filter
8.6.  L: Optimal search schemes
12.6.  L: Counting filters
14.6.  Exercise
15.6.  Exercise
19.6.  S: (C) 01*0 Seeds
21.6.  S: (A) Adaptive seeds
22.6  Review 4
26.6.  Exercise
28.6.  Myers Bitvector algorithm I
29.6.  Myers Bitvector algorithm II/ 
3.7.  Bloom Filter / Binning directories
5.7.  Exercise
6.7.  S: Byte Aligned Pattern Matching (B)
10.7.  Rehearsal
12.7  Review 5
13.7  Self study
17.7.  Oral examinations (13-16, 30 minute slots)
 (14:00 Gottlieb, 16 Uhr Kim)
18.7.  Oral examinations (13-16, 30 minute slots)
 (13:00 Matschkowski, 13:30 Krüger, 14:00 Pluhatsch, 14:30 Seiler, 15:00 Darvish)

 

 

 

Basic Course Info

Course No Course Type Hours
19401611 Seminar 2
19401601 Vorlesung 2
19401602 Übung 2

Time Span 17.04.2018 - 17.07.2018
Instructors
Hannes Hauswedell
Knut Reinert

Study Regulation

0089c_MA120 2014, MSc Informatik (Mono), 120 LPs
0262b_MA120 2012, MSc Bioinformatik (Mono), 120 LPs

Sequenzanalyse S18
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Main Events

Day Time Location Details
Tuesday 10-12 A3/SR 210 Seminarraum 2018-04-17 - 2018-07-17
Friday 14-16 A3/SR 210 Seminarraum 2018-04-27 - 2018-07-20

Accompanying Events

Day Time Location Details
Thursday 12-14 A3/SR 210 Seminarraum Übung 01
Sunday ? - ? Pseudotutorium zur Kapazitätsplanung - potentielle Übungsteilnehmer melden sich bitte hier an!

Sequenzanalyse S18
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