News:

March 10: Due to the corona virus this course will, at least at the start, take the form of an online course. There is still hope that we can switch to an in person format during the term - we'll keep you updated via this site. At the start, we will have regular online meetings and a substantial part of the course will be project work. Since this course is restricted to 12 participants, please make sure that you register not only here but in the Campus Management (CM), since only CM-registered participants are eligible for the course.

 

Content:

The course will give an introduction to the modeling of molecular networks using discrete/logical approaches as well as differential equations. The theoretical frameworks will be introduced and software tools presented. On the basis of suitable reasearch articles, the participants will conduct their own modeling project in small groups.

 

General Information

Lecturers: Jana Wolf, Heike Siebert

Topics: systems biology, boolean/logical modeling, ODE modeling

Target group: Students of the Master Bioinformatics program after the first term.

Tutors: Kirsten Thobe - kirsten.thobe@mdc-berlin.de

            Oscar Migueles - oscar.migueles@mdc-berlin.de

Requirements

During the course several smaller group projects need to be conducted and presented to obtain "active participation". The course grade will be given for the final project presentation.

Delivarables:

  • Software tutorials
  • 2 15-minute-presentations per group
  • slides of presentations (send via email to the lecturer before your talk)
  • documentation of your computational analysis

 

Time plan

 Date   Topic
 15.4.  Organisation and preliminaries
 22.4.  Formalism overview, Boolean modeling I
 29.4.  Modeling exercise, Boolean modeling II
 6.5.   BoolNet tutorial, Multi-valued modeling, projects
13.5.  Holiday
 20.5.  GINsim tutorial, project work
 27.5.  Application study, project work
 03.6.  Presentations: Logical modeling projects
 10.6.  ODE introduction
 17.6.  ODE lecture, ODE projects
 24.6.  Copasi tutorial, project work
 01.7.  lecture, project work
 08.7.  lecture, project work
 15.7. Presentations: ODE modeling projects