Part 2 Modelling using ODEs

Computational Systems Biology

Ausgerichtet von Jana Wolf

10:15 - 13:45 Donnerstag, 4. Juni 2020 (UTC+02:00) Amsterdam, Berlin, Bern, Rom, Stockholm, Wien

Tritt auf alle Donnerstag, gültig 4.6.2020 bis 16.7.2020 von 10:15 bis 13:45, (UTC+02:00) Amsterdam, Berlin, Bern, Rom, Stockholm, Wien

 

Meeting-Link:

https://fu-berlin.webex.com/fu-berlin/j.php?MTID=m3345aa325d7e9c74d70a91fc34308e6d

Meeting-Kennnummer:  121 806 1996

Passwort:   sysbio20

 

Über Videosystem beitreten

Wählen Sie 1218061996@fu-berlin.webex.com

Sie können auch 62.109.219.4 wählen und Ihre Meeting-Nummer eingeben.

 

Über Telefon beitreten

+49-69-2551-14400 Germany Toll 3

+49-619-6781-9736 Germany Toll

Zugriffscode: 121 806 1996

 

News:

April 30: Groups for the software projects:

BoolNet: Guillermo, Fatemeh, Satwant

GINsim: Anna Lena, Hannes, Larissa, Wiep

Copasi: Daria, Hee, Jacky, Ziyue

April 8: Due to the corona virus this course will take the form of an online course. We will have regular online meetings and a substantial part of the course will be project work. Since this course is restricted to 12 participants, please make sure that you register not only here but in the Campus Management (CM), since only CM-registered participants are eligible for the course.

March 20: Due to the corona virus the course will not start on April 16, but at the earliest on April 23. Please register in the Campus Management and check this website for more announcements.

 

Content:

The course focuses on the modeling of molecular networks using discrete/logical approaches as well as differential equations. The theoretical frameworks will be introduced and software tools presented. On the basis of suitable reasearch articles, the participants will conduct their own modeling project in small groups.

 

General Information

Lecturers: Heike Siebert, Jana Wolf

Topics: systems biology, boolean/logical modeling, ODE modeling

Target group: Students of the Master Bioinformatics program after the first term.

 

Requirements

During the course several smaller group projects need to be conducted and presented to obtain "active participation". The final grade will be given for the project presentation on  two case studies in modeling and analyzing molecular networks (logical/ODE).

Delivarables:

  • 30 minutes presentation per group (15 minutes per person and topic)
  • slides of presentation (send via email to both lecturers before your talk)
  • documentation of your computational analysis

 

Time plan

 Date   Topic
 23.4.  Formalism overview, Boolean modeling I
 30.4.  Modeling exercise, Boolean modeling II, software assignment
 7.5.   Software Tutorial I (BoolNet), Multi-valued modeling, case study       choices (logical modeling)
 14.5.  Software Tutorial II (GINsim), Case study assignment, project work
 21.5.  holiday
 28.5.  Flash talk, project work
4.6.  Introduction ODE modelling
11.6.  Intro ODE modelling: regulation, types of dynamics. Modeling excercise. Project assignment.
18.6. Theoretical background: stability of solutions. Software Tutorial (COPASI)
25.6.  Theory: oscillations. Project work
2.7.  Theory. Project work
9.7.  Student presentations
16.7.  Student presentations